March 20th, 2024
New paper is out
Our preprint characterizing mouse developmental enhancer—promoter interaction is published in Nature Genetics. Congratulations to our postdoc Zhuoxin Chen who led the study! See Papers.
December 11, 2023
New preprint
We are happy to share our new work Rapid and Quantitative Functional Interrogation of Human Enhancer Variant Activity in Live Mice. Huge congratulations to our MD/PhD student Ethan who led the project! See Papers.
March 3, 2023
Grace receives NIH F31 fellowship
Congratulations to our CMB graduate student Grace Bower, who has been awarded an NIH F31 – Ruth L. Kirschstein National Research Service Award from NICHD. Well done!
November 20, 2022
New preprint is out
We are happy to share our new preprint Widespread Increase in Enhancer-Promoter Interactions during Developmental Enhancer Activation in Mammals. Huge congratulations to our postdoc Zhuoxin Chen who led the study! See Papers.
October 6th, 2022
New grant
The Kvon lab has received NIH Director’s New Innovator Award. The grant will support our studies on long-range gene regulation over the next 5 years. See UCI press release.
August 2nd, 2022
We are hiring
We have an opening for a fully funded postdoctoral scholar position. If you are interested in studying mammalian gene regulation in sunny Southern California, apply here.
July 25th, 2022
Ethan receives NIH F30 fellowship
Congratulations to Ethan Hollingsworth, who has been awarded an NIH F30 – Ruth L. Kirschstein National Research Service Award from NICHD. Well done!
Research Interests
Specific non-coding regulatory DNA elements called enhancers regulate gene transcription during animal development. The Kvon lab investigates transcriptional regulation by enhancers using cutting-edge genomics, genome editing, and transgenic tools. We are particularly interested in studying the role of enhancers in development and evolution and how enhancer malfunction leads to congenital disease.