KVON LAB

Our paper describing the Range Extender element which is required and sufficient for long-range enhancer activation in published in Nature. Congratulations to our CMB student, Grace, who led the study! See Papers and Media Coverage.

We are happy to share our lab’s new work Enhancer Poising Enables Pathogenic Gene Activation by Noncoding Variants. Huge congratulations to our MD/PhD student Ethan who led the project! See Papers.

Congratulations to our graduate students Grace and Ethan for receiving the Howard A. Schneiderman Fellowship Award and Brian G. Atwood ’74 and Lynne H. Edminster Graduate Studies Endowment, respectively.

Huge congratulations to our PhD student Joshua Alcantara on receiving an F31 fellowship from NICHD to study “How gene regulatory redundancy ensures robustness of mammalian development”. Well done!

Congratulations to our Postdoc Zhuoxin for winning the Dean’s Early Career Research Excellence Award!

Our preprint describing a new dual-enSERT method to functionally test enhancer variants in vivo is published in Nature Communications. Congratulations to our MSTP student Ethan, who led the study! See Papers.

Our review on the genetic factors mediating long-range enhancer–promoter communication in mammalian development is out in Current Opinion in Genetics & Development. Congratulations to Grace. See Papers.​

Our lab’s research has been featured in the latest issue of The Scientist Digest. See The Scientist Interview.

We are grateful to the National Institute of Child Health and Human Development for supporting our studies on the mechanisms of enhancer mutations in congenital limb disorders over the next five years. See the UCI press release.