November 20, 2022
New preprint is out
We are happy to share our new preprint Widespread Increase in Enhancer-Promoter Interactions during Developmental Enhancer Activation in Mammals. Huge congratulations to our postdoc Zhuoxin Chen who led the study! See Papers.
July 25th, 2022
Ethan receives a NIH F30 fellowship
Congratulations to Ethan Hollingsworth, who has been awarded an NIH F30 – Ruth L. Kirschstein National Research Service Award from NICHD. Well done!
During animal development, a complex multicellular organism is formed from a single cell - the fertilized egg. This process is regulated through differential gene expression. Specific non-coding DNA elements called enhancers regulate gene transcription during animal development. The Kvon lab uses a combination of novel genomics tools, genome editing, and mouse developmental biology techniques to understand transcriptional regulation by enhancers in the context of mammalian development, evolution, and human congenital disorders.