April 30th, 2026
Zhuoxin receives K99 Award
Congratulations to our Postdoc Zhuoxin for winning the prestigious K99/R00 Pathway to Independence Award from the National Institute of Dental and Craniofacial Research (NIDCR). See the UCI press release.
April 27th, 2026
Yingying joins the lab
Welcome to our new postdoc Yingying Chen who joined our lab as a postdoctoral fellow after obtaining her Ph.D. from Shanghai Institute of Biochemistry and Cell Biology. See Members.
April 24th, 2026
Congratulations to Grace's Ph.D defense
Congratulations to Grace on completing her doctoral project on how Range Extender mediates long-distance enhancer regulatory activity! We wish her all the best as she continues to advance her research as a postdoctoral fellow in the Wysocka Lab.
Jan 5th, 2026
Zubair joins the lab
Welcome to our new postdoc Zubairul Islam who joined our lab as a postdoctoral fellow after obtaining his Ph.D. from National Centre for Biological Sciences. See Members.
July 22nd, 2025
Congratulations to Ethan's Ph.D defense
Celebrating a significant milestone in Ethan's MD-PhD journey: the successful defense of his doctoral dissertation, marking a pivotal achievement in his dual pursuit of medical and research excellence.
July 11th, 2025
Evgeny receives Hellman Fellowship
The lab receives a new grant from the Hellman Fellows Program. See the UCI press release.
July 2nd, 2025
Range Extender paper is published
Our paper describing the Range Extender element which is required and sufficient for long-range enhancer activation in published in Nature. Congratulations to our CMB student, Grace, who led the study! See Papers and Media Coverage.
June 22nd, 2025
New preprint
We are happy to share our lab’s new work Enhancer Poising Enables Pathogenic Gene Activation by Noncoding Variants. Huge congratulations to our MD/PhD student Ethan who led the project! See Papers.
June 5th, 2025
Congratulations to Ethan and Grace
Congratulations to our graduate students Grace and Ethan for receiving the Howard A. Schneiderman Fellowship Award and Brian G. Atwood ’74 and Lynne H. Edminster Graduate Studies Endowment, respectively.
March 27th, 2025
Joshua receives NIH F31 fellowship
Huge congratulations to our PhD student Joshua Alcantara on receiving an F31 fellowship from NICHD to study “How gene regulatory redundancy ensures robustness of mammalian development”. Well done!
Feb 10th, 2025
Zhuoxin receives Research Excellence Award
Congratulations to our Postdoc Zhuoxin for winning the Dean’s Early Career Research Excellence Award!
Jan 8th, 2025
Dual-enSERT paper is out
Our preprint describing a new dual-enSERT method to functionally test enhancer variants in vivo is published in Nature Communications. Congratulations to our MSTP student Ethan, who led the study! See Papers.
Research Interests
Specific non-coding regulatory DNA elements called enhancers regulate gene transcription during animal development. The Kvon lab investigates transcriptional regulation by enhancers using cutting-edge genomics, genome editing, and transgenic tools. We are particularly interested in studying the role of enhancers in development and evolution and how enhancer malfunction leads to congenital disease.