August 18th, 2021
Ethan joins the lab
After a successful summer rotation, Ethan Hollingsworth joins the Kvon lab for a PhD portion of his MD/PHD training. See Members.
June 17th, 2021
Grace Bower joins the lab
After a successful rotation, Grace joins the Kvon lab as an CMB graduate student. See Members.
June 7th, 2021
Ethan starts
Ethan Hollingsworth joins the Kvon lab for a summer rotation. See Members.
January 13th, 2021
Our review is out in Nature Reviews Genetics
Our review on the role of shadow enhancers in animal development, evolution and human disease written together with Zeba Wunderlich lab is out in Nature Reviews Genetics. See Papers.
News
Research Interests
During animal development, a complex multicellular organism is formed from a single cell - the fertilized egg. This process is regulated through differential gene expression. Specific non-coding DNA elements called enhancers regulate gene transcription during animal development. The Kvon lab uses a combination of novel genomics tools, genome editing, and mouse developmental biology techniques to understand transcriptional regulation by enhancers in the context of mammalian development, evolution, and human congenital disorders.